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P-31064

Indolicidin

Basic Information

Product Name
Indolicidin
Catalog No.
P-31064
CAS No.
140896-21-5
Sequence
H-ILPWKWPWWPWRR-NH2
Molecular Formula
C100H131N25O14
Molecular Weight
1906.32

Peptide Depictor

13 aa

H-H2N-I1L2P3W4K5W6P7W8W9P10W11R12R13
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShow

Sequence Overview

H-ILPWKWPWWPWRR-NH2
Length
13.00
Molecular Weight
1905.05 Da
Monoisotopic Mass
1905.05 Da
Estimated Net Charge
3.000
pI
14.00
Hydrophobicity GRAVY
-1.069

Physicochemical Properties

Basic Residue Ratio
23%
Acidic Residue Ratio
0%
Aromatic Residue Ratio
39%
Cys Count
0.000
Oxidation-Risk Residues
5.000
Asp-Gly / Asn-Gly
0.000

Solubility Analysis

Water Solubility
Poor
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
likely_good
Recommended Delivery Form
TFA
  • 疏水残基比例或连续疏水片段较高,水溶性可能较差

Calculation Parameters

Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.

PropertyParameterValueResult
Hemolysis Riskscore threshold0.9635————0.5640Hemolytic
Non-Foulingscore threshold0.03697————0.3892Fouling
Solubilityscore threshold0.9855————0.3290Soluble
Cell-Penetrating Potentialscore threshold0.7038————0.5028Cell-Penetrating
Toxicity Riskscore threshold0.9693————0.4900Toxic
PAMPA Passive Membrane Permeabilitypredicted value-6.022PAMPA prediction: lower passive membrane permeability
Caco-2 Permeabilitypredicted value-5.847Caco-2 prediction: higher cell-model permeability
Half-Life Model Outputmodel output0.9041Model output only, not in-vivo half-life