Basic Information
- Product Name
- Dermaseptin-S1
- Catalog No.
- P-31065
- CAS No.
- 136033-70-0
- Sequence
- H-ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ-OH
- Molecular Formula
- C152H257N43O44S2
- Molecular Weight
- 3455.11
Peptide Depictor
34 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ-OH
Length
34.00
Molecular Weight
3452.86 Da
Monoisotopic Mass
3452.86 Da
Estimated Net Charge
3.100
pI
10.58
Hydrophobicity GRAVY
0.1850
Physicochemical Properties
Basic Residue Ratio
12%
Acidic Residue Ratio
3%
Aromatic Residue Ratio
3%
Cys Count
0.000
Oxidation-Risk Residues
3.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Poor
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
likely_good
Recommended Delivery Form
TFA
- 疏水残基比例或连续疏水片段较高，水溶性可能较差
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.4091————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.009810————0.3892 | Fouling |
| Solubility | score threshold | 0.9861————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.6158————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.7672————0.4900 | Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -14.35 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.860 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 1.056 | Model output only, not in-vivo half-life |