Basic Information
- Product Name
- Arenicin-1
- Catalog No.
- P-31041
- CAS No.
- 808102-57-0
- Sequence
- H-RWCVYAYVRVRGVLVRYRRCW-OH {cyclo=disulfide:3-20}
- Molecular Formula
- C127H195N41O25S2
- Molecular Weight
- 2758.33
Peptide Depictor
21 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-RWCVYAYVRVRGVLVRYRRCW-OH {cyclo=disulfide:3-20}
Length
21.00
Molecular Weight
2756.45 Da
Monoisotopic Mass
2756.45 Da
Estimated Net Charge
6.000
pI
11.15
Hydrophobicity GRAVY
-0.07100
Physicochemical Properties
Basic Residue Ratio
29%
Acidic Residue Ratio
0%
Aromatic Residue Ratio
24%
Cys Count
2.000
Oxidation-Risk Residues
4.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Poor
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
likely_good
Recommended Delivery Form
HCl
- 疏水残基比例或连续疏水片段较高，水溶性可能较差
- 含多个Cys，溶解和氧化状态需同步控制
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.7580————0.5640 | Hemolytic |
| Non-Fouling | score threshold | 0.02369————0.3892 | Fouling |
| Solubility | score threshold | 0.9860————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.8346————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.6822————0.4900 | Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -8.129 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.847 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.7523 | Model output only, not in-vivo half-life |