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P-31040

Dermcidin-1L (human)

Basic Information

Product Name
Dermcidin-1L (human)
Catalog No.
P-31040
CAS No.
478898-18-9
Sequence
H-SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL-OH
Molecular Formula
C210H359N57O71
Molecular Weight
4818.50

Peptide Depictor

48 aa

H-HO-S1S2L3L4E5K6G7L8D9G10A11K12K13A14V15G16G17L18G19K20L21G22K23D24A25V26E27D28L29E30S31V32G33K34G35A36V37H38D39V40K41D42V43L44D45S46V47L48
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShow

Sequence Overview

H-SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL-OH
Length
48.00
Molecular Weight
4815.62 Da
Monoisotopic Mass
4815.62 Da
Estimated Net Charge
-1.900
pI
4.800
Hydrophobicity GRAVY
-0.02900

Physicochemical Properties

Basic Residue Ratio
15%
Acidic Residue Ratio
19%
Aromatic Residue Ratio
0%
Cys Count
0.000
Oxidation-Risk Residues
0.000
Asp-Gly / Asn-Gly
1.000

Solubility Analysis

Water Solubility
Moderate
Acidic Aqueous Compatibility
Use with caution
Basic Aqueous Compatibility
Suitable
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
TFA
  • 疏水残基比例偏高,建议先小量溶解测试

Calculation Parameters

Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.

PropertyParameterValueResult
Hemolysis Riskscore threshold0.1376————0.5640Non-hemolytic
Non-Foulingscore threshold0.01053————0.3892Fouling
Solubilityscore threshold0.9604————0.3290Soluble
Cell-Penetrating Potentialscore threshold0.7390————0.5028Cell-Penetrating
Toxicity Riskscore threshold0.1802————0.4900Non-Toxic
PAMPA Passive Membrane Permeabilitypredicted value-15.63PAMPA prediction: lower passive membrane permeability
Caco-2 Permeabilitypredicted value-5.853Caco-2 prediction: higher cell-model permeability
Half-Life Model Outputmodel output0.8042Model output only, not in-vivo half-life