Basic Information
- Product Name
- Cyclic L27-11
- Catalog No.
- P-31042
- CAS No.
- —
- Sequence
- TWLKKRRWKKAK[dP]P {cyclo=head_to_tail}
- Molecular Formula
- C87H143N27O16
- Molecular Weight
- 500.64
Peptide Depictor
14 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
TWLKKRRWKKAK[dP]P {cyclo=head_to_tail}
Length
14.00
Molecular Weight
1804.11 Da
Monoisotopic Mass
1804.11 Da
Estimated Net Charge
7.000
pI
12.52
Hydrophobicity GRAVY
-1.929
Physicochemical Properties
Basic Residue Ratio
50%
Acidic Residue Ratio
0%
Aromatic Residue Ratio
14%
Cys Count
0.000
Oxidation-Risk Residues
2.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Good
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
HCl
- 未发现明显溶解性风险
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.02405————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.03037————0.3892 | Fouling |
| Solubility | score threshold | 0.9861————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.8599————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.9971————0.4900 | Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -7.622 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.844 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.8361 | Model output only, not in-vivo half-life |