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P-31039

JB-95

Basic Information

Product Name
JB-95
Catalog No.
P-31039
CAS No.
—
Sequence
WRIRI[dR]WKRLRR[dP]P {cyclo=head_to_tail}
Molecular Formula
C92H153N35O15
Molecular Weight
500.64

Peptide Depictor

14 aa

W1R2I3R4I5Unknown building block: dRdR6W7K8R9L10R11R12Unknown building block: dPdP13P14Cyclization Methods: head_to_tail
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShow

Sequence Overview

WRIRI[dR]WKRLRR[dP]P {cyclo=head_to_tail}
Length
14.00
Molecular Weight
1970.22 Da
Monoisotopic Mass
1970.22 Da
Estimated Net Charge
6.000
pI
13.08
Hydrophobicity GRAVY
-1.214

Physicochemical Properties

Basic Residue Ratio
43%
Acidic Residue Ratio
0%
Aromatic Residue Ratio
14%
Cys Count
0.000
Oxidation-Risk Residues
2.000
Asp-Gly / Asn-Gly
0.000

Solubility Analysis

Water Solubility
Moderate
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
HCl
  • 疏水残基比例偏高,建议先小量溶解测试

Calculation Parameters

Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.

PropertyParameterValueResult
Hemolysis Riskscore threshold0.03794————0.5640Non-hemolytic
Non-Foulingscore threshold0.02535————0.3892Fouling
Solubilityscore threshold0.9861————0.3290Soluble
Cell-Penetrating Potentialscore threshold0.8932————0.5028Cell-Penetrating
Toxicity Riskscore threshold0.9201————0.4900Toxic
PAMPA Passive Membrane Permeabilitypredicted value-9.266PAMPA prediction: lower passive membrane permeability
Caco-2 Permeabilitypredicted value-5.842Caco-2 prediction: higher cell-model permeability
Half-Life Model Outputmodel output0.8361Model output only, not in-vivo half-life