Basic Information
- Product Name
- Tachyplesin I
- Catalog No.
- P-31018
- CAS No.
- 118231-04-2
- Sequence
- H-KWCFRVCYRGICYRRCR-NH2 {cyclo=disulfide:3-16} {cyclo=disulfide:7-12}
- Molecular Formula
- C99H154N34O20S4
- Molecular Weight
- 2263.79
Peptide Depictor
17 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-KWCFRVCYRGICYRRCR-NH2 {cyclo=disulfide:3-16} {cyclo=disulfide:7-12}
Length
17.00
Molecular Weight
2262.08 Da
Monoisotopic Mass
2262.08 Da
Estimated Net Charge
6.000
pI
10.59
Hydrophobicity GRAVY
-0.5180
Physicochemical Properties
Basic Residue Ratio
35%
Acidic Residue Ratio
0%
Aromatic Residue Ratio
24%
Cys Count
4.000
Oxidation-Risk Residues
5.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Moderate
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
HCl
- 疏水残基比例偏高，建议先小量溶解测试
- 含多个Cys，溶解和氧化状态需同步控制
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.4113————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.03614————0.3892 | Fouling |
| Solubility | score threshold | 0.9859————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.7913————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.8833————0.4900 | Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -8.501 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.844 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.7235 | Model output only, not in-vivo half-life |