Basic Information
- Product Name
- Human β-defensin-1
- Catalog No.
- P-31019
- CAS No.
- —
- Sequence
- H-DHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK-OH {cyclo=disulfide:5-34} {cyclo=disulfide:12-27} {cyclo=disulfide:17-35}
- Molecular Formula
- C167H262N48O50S6
- Molecular Weight
- 3928.56
Peptide Depictor
36 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-DHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK-OH {cyclo=disulfide:5-34} {cyclo=disulfide:12-27} {cyclo=disulfide:17-35}
Length
36.00
Molecular Weight
3925.73 Da
Monoisotopic Mass
3925.73 Da
Estimated Net Charge
4.100
pI
8.430
Hydrophobicity GRAVY
-0.2720
Physicochemical Properties
Basic Residue Ratio
14%
Acidic Residue Ratio
3%
Aromatic Residue Ratio
11%
Cys Count
6.000
Oxidation-Risk Residues
6.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Good
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
free
- 含多个Cys，溶解和氧化状态需同步控制
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.1489————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.01520————0.3892 | Fouling |
| Solubility | score threshold | 0.9855————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.4072————0.5028 | Non-Penetrating |
| Toxicity Risk | score threshold | 0.3503————0.4900 | Non-Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -10.72 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.850 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.7426 | Model output only, not in-vivo half-life |