Basic Information
- Product Name
- Protegrin-1
- Catalog No.
- P-31007
- CAS No.
- —
- Sequence
- H-RGGRLCYCRRRFCVCVGR-NH2 {cyclo=disulfide:6-15} {cyclo=disulfide:8-13}
- Molecular Formula
- C88H150N36O20S4
- Molecular Weight
- 2155.65
Peptide Depictor
18 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-RGGRLCYCRRRFCVCVGR-NH2 {cyclo=disulfide:6-15} {cyclo=disulfide:8-13}
Length
18.00
Molecular Weight
2154.06 Da
Monoisotopic Mass
2154.06 Da
Estimated Net Charge
6.000
pI
11.80
Hydrophobicity GRAVY
-0.2500
Physicochemical Properties
Basic Residue Ratio
33%
Acidic Residue Ratio
0%
Aromatic Residue Ratio
11%
Cys Count
4.000
Oxidation-Risk Residues
4.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Good
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
HCl
- 含多个Cys，溶解和氧化状态需同步控制
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.1906————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.04796————0.3892 | Fouling |
| Solubility | score threshold | 0.9859————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.8903————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.06095————0.4900 | Non-Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -10.04 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.840 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.7235 | Model output only, not in-vivo half-life |