Basic Information
- Product Name
- Larazotide acetate
- Catalog No.
- P-31006
- CAS No.
- —
- Sequence
- H-GGVLVQPG-OH
- Molecular Formula
- C32H55N9O10
- Molecular Weight
- 862.98
Peptide Depictor
8 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-GGVLVQPG-OH
Length
8.000
Molecular Weight
725.41 Da
Monoisotopic Mass
725.41 Da
Estimated Net Charge
0.000
pI
6.010
Hydrophobicity GRAVY
0.7380
Physicochemical Properties
Basic Residue Ratio
0%
Acidic Residue Ratio
0%
Aromatic Residue Ratio
0%
Cys Count
0.000
Oxidation-Risk Residues
0.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Moderate
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Suitable
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
TFA
- 疏水残基比例偏高，建议先小量溶解测试
- 净电荷较低且疏水性偏高，可能需要DMSO或酸性/碱性条件辅助
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.4356————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.2159————0.3892 | Fouling |
| Solubility | score threshold | 0.9736————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.5041————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.06163————0.4900 | Non-Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -11.24 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.849 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.9421 | Model output only, not in-vivo half-life |