Basic Information
- Product Name
- Magainin 2
- Catalog No.
- P-31008
- CAS No.
- —
- Sequence
- H-GIGKFLHSAKKFGKAFVGEIMNS-OH
- Molecular Formula
- C114H180N30O29S
- Molecular Weight
- 2466.94
Peptide Depictor
23 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-GIGKFLHSAKKFGKAFVGEIMNS-OH
Length
23.00
Molecular Weight
2465.33 Da
Monoisotopic Mass
2465.33 Da
Estimated Net Charge
3.100
pI
10.58
Hydrophobicity GRAVY
0.08300
Physicochemical Properties
Basic Residue Ratio
17%
Acidic Residue Ratio
4%
Aromatic Residue Ratio
13%
Cys Count
0.000
Oxidation-Risk Residues
1.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Moderate
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
TFA
- 疏水残基比例偏高，建议先小量溶解测试
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.7025————0.5640 | Hemolytic |
| Non-Fouling | score threshold | 0.08534————0.3892 | Fouling |
| Solubility | score threshold | 0.9570————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.06184————0.5028 | Non-Penetrating |
| Toxicity Risk | score threshold | 0.9356————0.4900 | Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -9.525 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.849 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.9482 | Model output only, not in-vivo half-life |