Basic Information
- Product Name
- Alamethicin
- Catalog No.
- P-31002
- CAS No.
- —
- Sequence
- Ac-[Aib]P[Aib]A[Aib]AQ[Aib]V[Aib]GL[Aib]PV[Aib][Aib]EQF-OL
- Molecular Formula
- C58H90N14O17
- Molecular Weight
- 1964.31
Peptide Depictor
20 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
Ac-[Aib]P[Aib]A[Aib]AQ[Aib]V[Aib]GL[Aib]PV[Aib][Aib]EQF-OL
Length
20.00
Molecular Weight
1963.11 Da
Monoisotopic Mass
1963.11 Da
Estimated Net Charge
-1.000
pI
Not calculated
Hydrophobicity GRAVY
0.2250
Physicochemical Properties
Basic Residue Ratio
0%
Acidic Residue Ratio
5%
Aromatic Residue Ratio
5%
Cys Count
0.000
Oxidation-Risk Residues
0.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Good
Acidic Aqueous Compatibility
Use with caution
Basic Aqueous Compatibility
Suitable
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
free
- 未发现明显溶解性风险
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.7958————0.5640 | Hemolytic |
| Non-Fouling | score threshold | 0.1009————0.3892 | Fouling |
| Solubility | score threshold | 0.9851————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.7697————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.0001913————0.4900 | Non-Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -8.279 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.843 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 1.397 | Model output only, not in-vivo half-life |