Basic Information
- Product Name
- LL-37, human
- Catalog No.
- P-31001
- CAS No.
- 154947-66-7
- Sequence
- H-LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES-OH
- Molecular Formula
- C205H340N60O53
- Molecular Weight
- 4493.33
Peptide Depictor
37 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES-OH
Length
37.00
Molecular Weight
4490.58 Da
Monoisotopic Mass
4490.58 Da
Estimated Net Charge
6.000
pI
11.14
Hydrophobicity GRAVY
-0.7240
Physicochemical Properties
Basic Residue Ratio
30%
Acidic Residue Ratio
14%
Aromatic Residue Ratio
11%
Cys Count
0.000
Oxidation-Risk Residues
0.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Moderate
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
HCl
- 疏水残基比例偏高，建议先小量溶解测试
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.6405————0.5640 | Hemolytic |
| Non-Fouling | score threshold | 0.03658————0.3892 | Fouling |
| Solubility | score threshold | 0.9839————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.6485————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.1069————0.4900 | Non-Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -10.69 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.849 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.8691 | Model output only, not in-vivo half-life |