A hormone secreted by thyroid C cells that regulates calcium and phosphate metabolism. It inhibits osteoclast activity and lowers blood calcium levels. Salmon calcitonin has higher activity than human calcitonin. Used for osteoporosis, Paget's disease, and hypercalcemia. Research-grade material is used in studies of bone metabolism, osteoclasts, calcium regulation, and osteoporosis.
Basic Information
- Product Name
- Calcitonin (Salmon)
- Catalog No.
- P-32059
- CAS No.
- 47931-85-1
- Sequence
- H-CSNLSTCVLSAYQLHKLQTYPRTNTGSGTP-NH2 {cyclo=disulfide:1-7}
- Molecular Formula
- C138H222N40O46S2
- Molecular Weight
- 3238.65
Peptide Depictor
30 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-CSNLSTCVLSAYQLHKLQTYPRTNTGSGTP-NH2 {cyclo=disulfide:1-7}
Length
30.00
Molecular Weight
3236.57 Da
Monoisotopic Mass
3236.57 Da
Estimated Net Charge
2.100
pI
9.610
Hydrophobicity GRAVY
-0.4230
Physicochemical Properties
Basic Residue Ratio
7%
Acidic Residue Ratio
0%
Aromatic Residue Ratio
7%
Cys Count
2.000
Oxidation-Risk Residues
2.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Good
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
free
- 含多个Cys，溶解和氧化状态需同步控制
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.3858————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.04215————0.3892 | Fouling |
| Solubility | score threshold | 0.4935————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.4276————0.5028 | Non-Penetrating |
| Toxicity Risk | score threshold | 0.03358————0.4900 | Non-Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -11.10 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.856 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.8253 | Model output only, not in-vivo half-life |