A neurohypophyseal hormone secreted by the hypothalamus. It promotes uterine contractions during labor and milk ejection during lactation. It is involved in social behavior, attachment, trust, and emotional regulation. It was the first neuropeptide to be sequenced and synthesized. Research-grade material is used in studies of reproductive physiology, social behavior, neuroendocrinology, and maternal-infant bonding.
Basic Information
- Product Name
- Oxytocin
- Catalog No.
- P-32060
- CAS No.
- 50-56-6
- Sequence
- H-CYIQNCPLG-NH2 {cyclo=disulfide:1-6}
- Molecular Formula
- C43H67N11O13S2
- Molecular Weight
- 1007.21
Peptide Depictor
9 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-CYIQNCPLG-NH2 {cyclo=disulfide:1-6}
Length
9.000
Molecular Weight
1006.44 Da
Monoisotopic Mass
1006.44 Da
Estimated Net Charge
0.000
pI
8.150
Hydrophobicity GRAVY
0.3330
Physicochemical Properties
Basic Residue Ratio
0%
Acidic Residue Ratio
0%
Aromatic Residue Ratio
11%
Cys Count
2.000
Oxidation-Risk Residues
2.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Moderate
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Suitable
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
TFA
- 净电荷较低且疏水性偏高，可能需要DMSO或酸性/碱性条件辅助
- 含多个Cys，溶解和氧化状态需同步控制
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.002222————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.02587————0.3892 | Fouling |
| Solubility | score threshold | 0.9742————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.6766————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.01969————0.4900 | Non-Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -9.516 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.840 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.7862 | Model output only, not in-vivo half-life |