A member of the thymosin family and an immunomodulatory peptide. Promotes T-cell differentiation and maturation and enhances cellular immune function. Used in chronic hepatitis B, immunodeficiency, and adjuvant tumor therapy. Research-grade material for studies of immunomodulation, T-cell development, tumor immunity, and antiviral immunity.
Basic Information
- Product Name
- Thymosin α-1
- Catalog No.
- P-32040
- CAS No.
- 62304-98-7
- Sequence
- Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN-OH
- Molecular Formula
- C127H213N33O54
- Molecular Weight
- 3108.28
Peptide Depictor
28 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN-OH
Length
28.00
Molecular Weight
3106.50 Da
Monoisotopic Mass
3106.50 Da
Estimated Net Charge
-5.000
pI
3.730
Hydrophobicity GRAVY
-1.029
Physicochemical Properties
Basic Residue Ratio
14%
Acidic Residue Ratio
32%
Aromatic Residue Ratio
0%
Cys Count
0.000
Oxidation-Risk Residues
0.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Good
Acidic Aqueous Compatibility
Use with caution
Basic Aqueous Compatibility
Suitable
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
acetate
- 未发现明显溶解性风险
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.004044————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.07511————0.3892 | Fouling |
| Solubility | score threshold | 0.9859————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.2518————0.5028 | Non-Penetrating |
| Toxicity Risk | score threshold | 0.02728————0.4900 | Non-Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -15.92 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.854 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.8906 | Model output only, not in-vivo half-life |