The major form of gastrin secreted by gastric antral G cells; stimulates gastric acid secretion and gastric mucosal growth. The C-terminal tetrapeptide Trp-Met-Asp-Phe-NH2 is the minimal active sequence. Research grade for studies of gastric acid secretion, gastric mucosal physiology, gastrin receptors, and digestive diseases.
Basic Information
- Product Name
- Gastrin-17 (Human)
- Catalog No.
- P-32024
- CAS No.
- 10047-33-3
- Sequence
- [Pyr]GPWLEEEEEAYGWMDF-NH2
- Molecular Formula
- C92H118N18O30S
- Molecular Weight
- 2098.23
Peptide Depictor
17 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
[Pyr]GPWLEEEEEAYGWMDF-NH2
Length
17.00
Molecular Weight
2096.85 Da
Monoisotopic Mass
2096.85 Da
Estimated Net Charge
-6.000
pI
3.410
Hydrophobicity GRAVY
-0.9530
Physicochemical Properties
Basic Residue Ratio
0%
Acidic Residue Ratio
35%
Aromatic Residue Ratio
24%
Cys Count
0.000
Oxidation-Risk Residues
3.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Moderate
Acidic Aqueous Compatibility
Use with caution
Basic Aqueous Compatibility
Suitable
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
acetate
- 疏水残基比例偏高，建议先小量溶解测试
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.5678————0.5640 | Hemolytic |
| Non-Fouling | score threshold | 0.02290————0.3892 | Fouling |
| Solubility | score threshold | 0.9841————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.5724————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.4906————0.4900 | Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -11.72 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.859 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.8552 | Model output only, not in-vivo half-life |