Bombesin-like peptide that stimulates gastrin release, gastric acid secretion, and smooth muscle contraction. It is also distributed in the nervous system and is involved in various physiological functions. The C-terminal decapeptide (GRP-10) is the core region for receptor binding. Research grade, for studies of GRP receptors, digestive physiology, neuropeptides, and oncology.
Basic Information
- Product Name
- Gastrin Releasing Peptide (GRP)
- Catalog No.
- P-32023
- CAS No.
- 93755-85-2
- Sequence
- H-VPLPAGGGTVLTKMYPRGNHWAVGHLM-NH2
- Molecular Formula
- C130H203N37O32S2
- Molecular Weight
- 2859.42
Peptide Depictor
27 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-VPLPAGGGTVLTKMYPRGNHWAVGHLM-NH2
Length
27.00
Molecular Weight
2857.50 Da
Monoisotopic Mass
2857.50 Da
Estimated Net Charge
2.200
pI
11.61
Hydrophobicity GRAVY
0.1000
Physicochemical Properties
Basic Residue Ratio
7%
Acidic Residue Ratio
0%
Aromatic Residue Ratio
7%
Cys Count
0.000
Oxidation-Risk Residues
3.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Moderate
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
TFA
- 疏水残基比例偏高，建议先小量溶解测试
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.2718————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.008731————0.3892 | Fouling |
| Solubility | score threshold | 0.9855————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.7190————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.3981————0.4900 | Non-Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -12.72 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.859 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.7976 | Model output only, not in-vivo half-life |