A hormone secreted by duodenal S cells that stimulates pancreatic duct cells to secrete water and bicarbonate. Used in pancreatic function diagnostics. Belongs to the glucagon/secretin family. Research-grade material for studies of pancreatic function, digestive physiology, and mechanisms of pancreatic fluid secretion.
Basic Information
- Product Name
- Secretin (Human)
- Catalog No.
- P-32021
- CAS No.
- 17034-35-4
- Sequence
- H-HSDGTFTSELSRLRDSARLQRLLQGLV-NH2
- Molecular Formula
- C130H219N43O42
- Molecular Weight
- 3055.45
Peptide Depictor
27 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-HSDGTFTSELSRLRDSARLQRLLQGLV-NH2
Length
27.00
Molecular Weight
3053.65 Da
Monoisotopic Mass
3053.65 Da
Estimated Net Charge
1.100
pI
12.01
Hydrophobicity GRAVY
-0.4630
Physicochemical Properties
Basic Residue Ratio
15%
Acidic Residue Ratio
11%
Aromatic Residue Ratio
4%
Cys Count
0.000
Oxidation-Risk Residues
0.000
Asp-Gly / Asn-Gly
1.000
Solubility Analysis
Water Solubility
Good
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
free
- 未发现明显溶解性风险
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.1274————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.02235————0.3892 | Fouling |
| Solubility | score threshold | 0.9861————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.8054————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.1144————0.4900 | Non-Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -16.23 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.857 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.7269 | Model output only, not in-vivo half-life |