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P-32019

Somatostatin-28 (SST-28)

The long form of somatostatin, with 14 amino acids extended at the N-terminus of SST-14. It is primarily secreted by the intestine and has a stronger inhibitory effect on pancreatic islets. Its half-life is also very short. Research-grade material for studies of somatostatin isoforms, tissue specificity, and endocrine regulation.

Basic Information

Product Name
Somatostatin-28 (SST-28)
Catalog No.
P-32019
CAS No.
—
Sequence
H-SANSNPAMAPRERKAGCKNFFWKTFTSC-OH {cyclo=disulfide:17-28}
Molecular Formula
C137H209N41O39S3
Molecular Weight
3148.60

Peptide Depictor

28 aa

H--OHS1A2N3S4N5P6A7M8A9P10R11E12R13K14A15G16C17K18N19F20F21W22K23T24F25T26S27C28Cyclization Methods: S-S
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShow

Sequence Overview

H-SANSNPAMAPRERKAGCKNFFWKTFTSC-OH {cyclo=disulfide:17-28}
Length
28.00
Molecular Weight
3146.46 Da
Monoisotopic Mass
3146.46 Da
Estimated Net Charge
4.000
pI
10.34
Hydrophobicity GRAVY
-0.7320

Physicochemical Properties

Basic Residue Ratio
18%
Acidic Residue Ratio
4%
Aromatic Residue Ratio
14%
Cys Count
2.000
Oxidation-Risk Residues
4.000
Asp-Gly / Asn-Gly
0.000

Solubility Analysis

Water Solubility
Good
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
free
  • 含多个Cys,溶解和氧化状态需同步控制

Calculation Parameters

Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.

PropertyParameterValueResult
Hemolysis Riskscore threshold0.03396————0.5640Non-hemolytic
Non-Foulingscore threshold0.04118————0.3892Fouling
Solubilityscore threshold0.9854————0.3290Soluble
Cell-Penetrating Potentialscore threshold0.7264————0.5028Cell-Penetrating
Toxicity Riskscore threshold0.2682————0.4900Non-Toxic
PAMPA Passive Membrane Permeabilitypredicted value-10.72PAMPA prediction: lower passive membrane permeability
Caco-2 Permeabilitypredicted value-5.852Caco-2 prediction: higher cell-model permeability
Half-Life Model Outputmodel output0.7961Model output only, not in-vivo half-life