Growth hormone-releasing hormone secreted by the hypothalamus, with a full length of 44 amino acids. It stimulates pituitary synthesis and release of growth hormone through the GHRH receptor. Short half-life (approximately 7–50 minutes). Research-grade material for studies of growth hormone axis regulation, endocrine physiology, and the hypothalamic-pituitary axis.
Basic Information
- Product Name
- GHRH (Human) (1-44)
- Catalog No.
- P-32015
- CAS No.
- 83930-13-6
- Sequence
- H-YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARL-NH2
- Molecular Formula
- C215H357N71O67S
- Molecular Weight
- 5039.72
Peptide Depictor
44 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARL-NH2
Length
44.00
Molecular Weight
5036.66 Da
Monoisotopic Mass
5036.66 Da
Estimated Net Charge
4.000
pI
11.33
Hydrophobicity GRAVY
-0.7980
Physicochemical Properties
Basic Residue Ratio
18%
Acidic Residue Ratio
9%
Aromatic Residue Ratio
7%
Cys Count
0.000
Oxidation-Risk Residues
1.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Moderate
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
TFA
- 疏水残基比例偏高，建议先小量溶解测试
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.5037————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.003321————0.3892 | Fouling |
| Solubility | score threshold | 0.9852————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.3367————0.5028 | Non-Penetrating |
| Toxicity Risk | score threshold | 0.05298————0.4900 | Non-Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -12.28 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.854 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 1.041 | Model output only, not in-vivo half-life |