Basic Information
- Product Name
- Hepcidin-25 (human)
- Catalog No.
- P-31068
- CAS No.
- 1356390-47-0
- Sequence
- H-DTHFPICIFCCGCCHRSKCGMCCKT {cyclo=disulfide:7-23} {cyclo=disulfide:10-13} {cyclo=disulfide:11-19} {cyclo=disulfide:14-22}
- Molecular Formula
- C113H178N34O31S9
- Molecular Weight
- 2789.41
Peptide Depictor
25 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-DTHFPICIFCCGCCHRSKCGMCCKT {cyclo=disulfide:7-23} {cyclo=disulfide:10-13} {cyclo=disulfide:11-19} {cyclo=disulfide:14-22}
Length
25.00
Molecular Weight
2787.03 Da
Monoisotopic Mass
2787.03 Da
Estimated Net Charge
2.200
pI
7.710
Hydrophobicity GRAVY
0.3880
Physicochemical Properties
Basic Residue Ratio
12%
Acidic Residue Ratio
4%
Aromatic Residue Ratio
8%
Cys Count
8.000
Oxidation-Risk Residues
9.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Good
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
free
- 含多个Cys，溶解和氧化状态需同步控制
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.1770————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.03110————0.3892 | Fouling |
| Solubility | score threshold | 0.9861————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.5999————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.04189————0.4900 | Non-Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -10.57 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.845 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.8422 | Model output only, not in-vivo half-life |