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P-31022

KR-12 (human)

Basic Information

Product Name
KR-12 (human)
Catalog No.
P-31022
CAS No.
1218951-51-9
Sequence
H-KRIVQRIKDFLR-NH2
Molecular Formula
C71H126N24O16
Molecular Weight
1570.95

Peptide Depictor

12 aa

H--NH2K1R2I3V4Q5R6I7K8D9F10L11R12
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShow

Sequence Overview

H-KRIVQRIKDFLR-NH2
Length
12.00
Molecular Weight
1569.99 Da
Monoisotopic Mass
1569.99 Da
Estimated Net Charge
4.000
pI
12.79
Hydrophobicity GRAVY
-0.7080

Physicochemical Properties

Basic Residue Ratio
42%
Acidic Residue Ratio
8%
Aromatic Residue Ratio
8%
Cys Count
0.000
Oxidation-Risk Residues
0.000
Asp-Gly / Asn-Gly
0.000

Solubility Analysis

Water Solubility
Moderate
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
HCl
  • 疏水残基比例偏高,建议先小量溶解测试

Calculation Parameters

Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.

PropertyParameterValueResult
Hemolysis Riskscore threshold0.2769————0.5640Non-hemolytic
Non-Foulingscore threshold0.01912————0.3892Fouling
Solubilityscore threshold0.9860————0.3290Soluble
Cell-Penetrating Potentialscore threshold0.7759————0.5028Cell-Penetrating
Toxicity Riskscore threshold0.8743————0.4900Toxic
PAMPA Passive Membrane Permeabilitypredicted value-12.60PAMPA prediction: lower passive membrane permeability
Caco-2 Permeabilitypredicted value-5.847Caco-2 prediction: higher cell-model permeability
Half-Life Model Outputmodel output0.6798Model output only, not in-vivo half-life