Potent growth hormone-releasing peptide and GHSR agonist, more potent than GHRP-6. D-2-Me-Trp modification enhances metabolic stability. Research grade for studies of growth hormone release, cardioprotection, and GHSR receptor pharmacology.
Basic Information
- Product Name
- Hexarelin
- Catalog No.
- P-32012
- CAS No.
- —
- Sequence
- H-H[d2MeW]AW[dF]K-NH2
- Molecular Formula
- C35H45N9O6
- Molecular Weight
- 1248.43
Peptide Depictor
6 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-H[d2MeW]AW[dF]K-NH2
Length
6.000
Molecular Weight
886.46 Da
Monoisotopic Mass
886.46 Da
Estimated Net Charge
1.100
pI
14.00
Hydrophobicity GRAVY
-1.033
Physicochemical Properties
Basic Residue Ratio
17%
Acidic Residue Ratio
0%
Aromatic Residue Ratio
17%
Cys Count
0.000
Oxidation-Risk Residues
1.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Good
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
free
- 未发现明显溶解性风险
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.01850————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.1124————0.3892 | Fouling |
| Solubility | score threshold | 0.9861————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.5944————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.8729————0.4900 | Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -8.105 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.858 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.7985 | Model output only, not in-vivo half-life |