The peptide segment in proinsulin that connects the A and B chains and is secreted in equimolar amounts with insulin. It has no insulin-like biological activity, but can serve as a marker of endogenous insulin secretion. Research-grade material is used for assessment of pancreatic beta-cell function, diabetes classification, and studies of insulin secretion mechanisms.
Basic Information
- Product Name
- C-Peptide (Human)
- Catalog No.
- P-32008
- CAS No.
- 33017-11-7
- Sequence
- H-EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ-OH
- Molecular Formula
- C129H211N35O48
- Molecular Weight
- 3020.30
Peptide Depictor
31 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ-OH
Length
31.00
Molecular Weight
3018.51 Da
Monoisotopic Mass
3018.51 Da
Estimated Net Charge
-5.000
pI
2.800
Hydrophobicity GRAVY
-0.08100
Physicochemical Properties
Basic Residue Ratio
0%
Acidic Residue Ratio
16%
Aromatic Residue Ratio
0%
Cys Count
0.000
Oxidation-Risk Residues
0.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Moderate
Acidic Aqueous Compatibility
Use with caution
Basic Aqueous Compatibility
Suitable
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
TFA
- 疏水残基比例偏高，建议先小量溶解测试
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.02887————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.01281————0.3892 | Fouling |
| Solubility | score threshold | 0.9856————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.6926————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.07542————0.4900 | Non-Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -19.81 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.860 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 1.013 | Model output only, not in-vivo half-life |