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R-11006

Dopamine.HCl (d4)

Stable isotope standard for analytical research and method development.

Module Type
Stable Isotope Standards
Category
Hormones
CAS
203633-19-6
Unlabeled CAS
62-31-7
PubChem CID
45039112
Molecular Formula
C8H8D4ClNO2
Molecular Weight
193.66
AI Isotope Property & Application AnalysisShow

Isotope Summary

Labels
D4
Labeled atoms
4
Isotope positions
Partially confirmed in structure
Calculation reliability
Medium, some information should be confirmed

Mass & MS Parameters

Unlabeled exact mass
189.055656 Da
Labeled exact mass
193.080763 Da
Exact mass shift
4.025107 Da
Nominal mass shift
4
Ionm/zStatus
[M+H]+194.08804Theoretical
[M+Na]+216.069981Theoretical
[M+NH4]+211.114586Theoretical
[M-H]-192.073487Theoretical

Label Stability

Overall
Moderate risk
Calculation reliability
Medium, some information should be confirmed
  • Carbon-bound deuterium is evaluated by local chemical environment; isotope effects should still be checked experimentally.

Internal Standard Suitability

Rating
Medium
Chromatographic similarity
Possible isotope effect
Natural isotope overlap
Low
  • Exact mass separation is 4.025107 Da; MS channel separation should be verified in the final method.
  • The unlabeled parent mass was derived from the isotope structure because a curated parent structure was not matched.
  • Overall suitability: Medium.

Recommended Applications

LC-MS/MS Quantitative Internal Standard
Recommended

LC-MS/MS Quantitative Internal Standard is classified as Recommended based on isotope mapping, mass separation, and label-stability rules.

Isotope Dilution Mass Spectrometry
Recommended

Isotope Dilution Mass Spectrometry is classified as Recommended based on isotope mapping, mass separation, and label-stability rules.

GC-MS Internal Standard
Possible

GC-MS Internal Standard is classified as Possible based on isotope mapping, mass separation, and label-stability rules.

Bioanalytical Method Development
Recommended

Bioanalytical Method Development is classified as Recommended based on isotope mapping, mass separation, and label-stability rules.

AI Interpretation

This analysis is based on isotope-aware structure data. The compound contains D4, with an exact mass shift of 4.025107 Da. Label stability is assessed as Moderate risk, and internal-standard suitability is Medium. These results support analytical method development and require experimental validation.

AI-assisted analytical guidance is intended for method-development support. Actual isotope stability, chromatographic behavior, fragmentation and MRM transitions should be experimentally validated.