Basic Information
- Product Name
- Defensin HNP-3 human
- Catalog No.
- P-31059
- CAS No.
- 136661-76-2
- Sequence
- H-DCYCRIPACIAGERRYGTCIYQGRLWAFCC-OH {cyclo=disulfide:2-30} {cyclo=disulfide:4-19} {cyclo=disulfide:9-29}
- Molecular Formula
- C151H228N44O40S6
- Molecular Weight
- 3486.10
Peptide Depictor
30 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
H-DCYCRIPACIAGERRYGTCIYQGRLWAFCC-OH {cyclo=disulfide:2-30} {cyclo=disulfide:4-19} {cyclo=disulfide:9-29}
Length
30.00
Molecular Weight
3483.50 Da
Monoisotopic Mass
3483.50 Da
Estimated Net Charge
2.000
pI
7.870
Hydrophobicity GRAVY
0.1230
Physicochemical Properties
Basic Residue Ratio
13%
Acidic Residue Ratio
7%
Aromatic Residue Ratio
17%
Cys Count
6.000
Oxidation-Risk Residues
7.000
Asp-Gly / Asn-Gly
0.000
Solubility Analysis
Water Solubility
Moderate
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
TFA
- 疏水残基比例偏高，建议先小量溶解测试
- 含多个Cys，溶解和氧化状态需同步控制
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.2325————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.02043————0.3892 | Fouling |
| Solubility | score threshold | 0.9860————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.7783————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.5256————0.4900 | Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -11.24 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.850 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.7584 | Model output only, not in-vivo half-life |