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P-31057

LL-37 FK-13

Basic Information

Product Name
LL-37 FK-13
Catalog No.
P-31057
CAS No.
717919-68-1
Sequence
H-FKRIVQRIKDFLR-OH
Molecular Formula
C80H135N25O17
Molecular Weight
1719.11

Peptide Depictor

13 aa

H-HO-F1K2R3I4V5Q6R7I8K9D10F11L12R13
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShow

Sequence Overview

H-FKRIVQRIKDFLR-OH
Length
13.00
Molecular Weight
1718.05 Da
Monoisotopic Mass
1718.05 Da
Estimated Net Charge
4.000
pI
12.21
Hydrophobicity GRAVY
-0.4380

Physicochemical Properties

Basic Residue Ratio
39%
Acidic Residue Ratio
8%
Aromatic Residue Ratio
15%
Cys Count
0.000
Oxidation-Risk Residues
0.000
Asp-Gly / Asn-Gly
0.000

Solubility Analysis

Water Solubility
Poor
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
likely_good
Recommended Delivery Form
HCl
  • 疏水残基比例或连续疏水片段较高,水溶性可能较差

Calculation Parameters

Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.

PropertyParameterValueResult
Hemolysis Riskscore threshold0.02210————0.5640Non-hemolytic
Non-Foulingscore threshold0.01621————0.3892Fouling
Solubilityscore threshold0.9861————0.3290Soluble
Cell-Penetrating Potentialscore threshold0.7823————0.5028Cell-Penetrating
Toxicity Riskscore threshold0.6965————0.4900Toxic
PAMPA Passive Membrane Permeabilitypredicted value-10.33PAMPA prediction: lower passive membrane permeability
Caco-2 Permeabilitypredicted value-5.848Caco-2 prediction: higher cell-model permeability
Half-Life Model Outputmodel output0.6927Model output only, not in-vivo half-life