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P-31052

IDR-1018

Basic Information

Product Name
IDR-1018
Catalog No.
P-31052
CAS No.
1453221-07-2
Sequence
H-VRLIVAVRIWRR-NH2
Molecular Formula
C71H125N25O13
Molecular Weight
1535.96

Peptide Depictor

12 aa

H--NH2V1R2L3I4V5A6V7R8I9W10R11R12
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShow

Sequence Overview

H-VRLIVAVRIWRR-NH2
Length
12.00
Molecular Weight
1535.00 Da
Monoisotopic Mass
1535.00 Da
Estimated Net Charge
4.000
pI
14.00
Hydrophobicity GRAVY
0.6920

Physicochemical Properties

Basic Residue Ratio
33%
Acidic Residue Ratio
0%
Aromatic Residue Ratio
8%
Cys Count
0.000
Oxidation-Risk Residues
1.000
Asp-Gly / Asn-Gly
0.000

Solubility Analysis

Water Solubility
Poor
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
likely_good
Recommended Delivery Form
HCl
  • 疏水残基比例或连续疏水片段较高,水溶性可能较差

Calculation Parameters

Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.

PropertyParameterValueResult
Hemolysis Riskscore threshold0.2771————0.5640Non-hemolytic
Non-Foulingscore threshold0.01370————0.3892Fouling
Solubilityscore threshold0.9856————0.3290Soluble
Cell-Penetrating Potentialscore threshold0.7824————0.5028Cell-Penetrating
Toxicity Riskscore threshold0.9623————0.4900Toxic
PAMPA Passive Membrane Permeabilitypredicted value-11.76PAMPA prediction: lower passive membrane permeability
Caco-2 Permeabilitypredicted value-5.848Caco-2 prediction: higher cell-model permeability
Half-Life Model Outputmodel output0.7194Model output only, not in-vivo half-life