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P-31034

PMAP-23

Basic Information

Product Name
PMAP-23
Catalog No.
P-31034
CAS No.
350019-43-1
Sequence
H-RIIDLLWRVRRPQKPKFVTV-NH2
Molecular Formula
C118H198N36O25
Molecular Weight
2520.12

Peptide Depictor

20 aa

H-H2N-R1I2I3D4L5L6W7R8V9R10R11P12Q13K14P15K16F17V18T19V20
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShow

Sequence Overview

H-RIIDLLWRVRRPQKPKFVTV-NH2
Length
20.00
Molecular Weight
2518.55 Da
Monoisotopic Mass
2518.55 Da
Estimated Net Charge
5.000
pI
12.96
Hydrophobicity GRAVY
-0.2800

Physicochemical Properties

Basic Residue Ratio
30%
Acidic Residue Ratio
5%
Aromatic Residue Ratio
10%
Cys Count
0.000
Oxidation-Risk Residues
1.000
Asp-Gly / Asn-Gly
0.000

Solubility Analysis

Water Solubility
Poor
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
likely_good
Recommended Delivery Form
HCl
  • 疏水残基比例或连续疏水片段较高,水溶性可能较差

Calculation Parameters

Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.

PropertyParameterValueResult
Hemolysis Riskscore threshold0.1236————0.5640Non-hemolytic
Non-Foulingscore threshold0.01194————0.3892Fouling
Solubilityscore threshold0.9859————0.3290Soluble
Cell-Penetrating Potentialscore threshold0.5813————0.5028Cell-Penetrating
Toxicity Riskscore threshold0.6026————0.4900Toxic
PAMPA Passive Membrane Permeabilitypredicted value-8.884PAMPA prediction: lower passive membrane permeability
Caco-2 Permeabilitypredicted value-5.843Caco-2 prediction: higher cell-model permeability
Half-Life Model Outputmodel output0.7365Model output only, not in-vivo half-life