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P-30041

Decapeptide-4

Anti-wrinkle

Basic Information

Product Name
Decapeptide-4
Catalog No.
P-30041
CAS No.
2227218-71-3
Sequence
H-CDLRRLEMYC-OH
Molecular Formula
C53H88N16O16S3
Molecular Weight
1301.58

Peptide Depictor

10 aa

H--OHC1D2L3R4R5L6E7M8Y9C10
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShow

Sequence Overview

H-CDLRRLEMYC-OH
Length
10.00
Molecular Weight
1300.57 Da
Monoisotopic Mass
1300.57 Da
Estimated Net Charge
0.000
pI
6.110
Hydrophobicity GRAVY
-0.2800

Physicochemical Properties

Basic Residue Ratio
20%
Acidic Residue Ratio
20%
Aromatic Residue Ratio
10%
Cys Count
2.000
Oxidation-Risk Residues
3.000
Asp-Gly / Asn-Gly
0.000

Solubility Analysis

Water Solubility
Moderate
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Suitable
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
TFA
  • 疏水残基比例偏高,建议先小量溶解测试
  • 净电荷较低且疏水性偏高,可能需要DMSO或酸性/碱性条件辅助
  • 含多个Cys,溶解和氧化状态需同步控制

Calculation Parameters

Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.

PropertyParameterValueResult
Hemolysis Riskscore threshold0.04513————0.5640Non-hemolytic
Non-Foulingscore threshold0.04590————0.3892Fouling
Solubilityscore threshold0.9861————0.3290Soluble
Cell-Penetrating Potentialscore threshold0.6666————0.5028Cell-Penetrating
Toxicity Riskscore threshold0.9197————0.4900Toxic
PAMPA Passive Membrane Permeabilitypredicted value-12.41PAMPA prediction: lower passive membrane permeability
Caco-2 Permeabilitypredicted value-5.856Caco-2 prediction: higher cell-model permeability
Half-Life Model Outputmodel output0.7523Model output only, not in-vivo half-life