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P-30015

Pentapeptide-18

Anti-Wrinkle/Neurotransmitter-Inhibiting Peptide

Basic Information

Product Name
Pentapeptide-18
Catalog No.
P-30015
CAS No.
64963-01-5
Sequence
H-Y[dA]GFL-OH
Molecular Formula
C29H39N5O7
Molecular Weight
569.66

Peptide Depictor

5 aa

H--OHY1Unknown building block: dAdA2G3F4L5
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShow

Sequence Overview

H-Y[dA]GFL-OH
Length
5.000
Molecular Weight
569.28 Da
Monoisotopic Mass
569.28 Da
Estimated Net Charge
0.000
pI
5.940
Hydrophobicity GRAVY
0.9800

Physicochemical Properties

Basic Residue Ratio
0%
Acidic Residue Ratio
0%
Aromatic Residue Ratio
40%
Cys Count
0.000
Oxidation-Risk Residues
0.000
Asp-Gly / Asn-Gly
0.000

Solubility Analysis

Water Solubility
Poor
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Suitable
DMSO Solubility Tendency
likely_good
Recommended Delivery Form
TFA
  • 疏水残基比例或连续疏水片段较高,水溶性可能较差
  • 净电荷较低且疏水性偏高,可能需要DMSO或酸性/碱性条件辅助

Calculation Parameters

Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.

PropertyParameterValueResult
Hemolysis Riskscore threshold0.001771————0.5640Non-hemolytic
Non-Foulingscore threshold0.09326————0.3892Fouling
Solubilityscore threshold0.9840————0.3290Soluble
Cell-Penetrating Potentialscore threshold0.8026————0.5028Cell-Penetrating
Toxicity Riskscore threshold0.08884————0.4900Non-Toxic
PAMPA Passive Membrane Permeabilitypredicted value-9.330PAMPA prediction: lower passive membrane permeability
Caco-2 Permeabilitypredicted value-5.860Caco-2 prediction: higher cell-model permeability
Half-Life Model Outputmodel output0.8852Model output only, not in-vivo half-life