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P-30012

Dipeptide-2

Under-Eye Bag Reduction / Eye Care

Basic Information

Product Name
Dipeptide-2
Catalog No.
P-30012
CAS No.
24587-37-9
Sequence
H-VW-OH
Molecular Formula
C16H21N3O3
Molecular Weight
303.36

Peptide Depictor

2 aa

H--OHV1W2
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShow

Sequence Overview

H-VW-OH
Length
2.000
Molecular Weight
303.16 Da
Monoisotopic Mass
303.16 Da
Estimated Net Charge
0.000
pI
6.010
Hydrophobicity GRAVY
1.650

Physicochemical Properties

Basic Residue Ratio
0%
Acidic Residue Ratio
0%
Aromatic Residue Ratio
50%
Cys Count
0.000
Oxidation-Risk Residues
1.000
Asp-Gly / Asn-Gly
0.000

Solubility Analysis

Water Solubility
Poor
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Suitable
DMSO Solubility Tendency
likely_good
Recommended Delivery Form
TFA
  • 疏水残基比例或连续疏水片段较高,水溶性可能较差
  • 净电荷较低且疏水性偏高,可能需要DMSO或酸性/碱性条件辅助

Calculation Parameters

Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.

PropertyParameterValueResult
Hemolysis Riskscore threshold1.000————0.5640Hemolytic
Non-Foulingscore threshold0.08247————0.3892Fouling
Solubilityscore threshold0.9859————0.3290Soluble
Cell-Penetrating Potentialscore threshold0.7486————0.5028Cell-Penetrating
Toxicity Riskscore threshold0.6235————0.4900Toxic
PAMPA Passive Membrane Permeabilitypredicted value-5.796PAMPA prediction: higher passive membrane permeability
Caco-2 Permeabilitypredicted value-5.819Caco-2 prediction: higher cell-model permeability
Half-Life Model Outputmodel output0.9787Model output only, not in-vivo half-life