Anti-Wrinkle/Neurotransmitter-Inhibiting Peptide
Basic Information
- Product Name
- Conotoxin
- Catalog No.
- P-30007
- CAS No.
- —
- Sequence
- [Pyr]GCCNGPKGCSSKWCRDHARCC-NH2 {cyclo=disulfide:3-15} {cyclo=disulfide:4-21} {cyclo=disulfide:10-22}
- Molecular Formula
- C87H139N33O27S6
- Molecular Weight
- 2743.10
Peptide Depictor
22 aa
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Natural AA
Non-natural AA
Linker-like
Side-chain mod
Unknown
Acidic
Basic
Hydrophobic
Aromatic
Modified
Disulfide bond
Cyclization bond
AI-Assisted Peptide Property AnalysisShowHide
Sequence Overview
[Pyr]GCCNGPKGCSSKWCRDHARCC-NH2 {cyclo=disulfide:3-15} {cyclo=disulfide:4-21} {cyclo=disulfide:10-22}
Length
22.00
Molecular Weight
2373.89 Da
Monoisotopic Mass
2373.89 Da
Estimated Net Charge
3.100
pI
8.460
Hydrophobicity GRAVY
-0.7050
Physicochemical Properties
Basic Residue Ratio
18%
Acidic Residue Ratio
5%
Aromatic Residue Ratio
5%
Cys Count
6.000
Oxidation-Risk Residues
7.000
Asp-Gly / Asn-Gly
1.000
Solubility Analysis
Water Solubility
Good
Acidic Aqueous Compatibility
Suitable
Basic Aqueous Compatibility
Use with caution
DMSO Solubility Tendency
Moderate
Recommended Delivery Form
free
- 含多个Cys，溶解和氧化状态需同步控制
Calculation Parameters
Calculated parameters are model predictions for research design, candidate comparison, and project evaluation only. They are not experimental measurements or final synthesis outcomes.
| Property | Parameter | Value | Result |
|---|---|---|---|
| Hemolysis Risk | score threshold | 0.01289————0.5640 | Non-hemolytic |
| Non-Fouling | score threshold | 0.03539————0.3892 | Fouling |
| Solubility | score threshold | 0.9853————0.3290 | Soluble |
| Cell-Penetrating Potential | score threshold | 0.7710————0.5028 | Cell-Penetrating |
| Toxicity Risk | score threshold | 0.1546————0.4900 | Non-Toxic |
| PAMPA Passive Membrane Permeability | predicted value | -12.27 | PAMPA prediction: lower passive membrane permeability |
| Caco-2 Permeability | predicted value | -5.844 | Caco-2 prediction: higher cell-model permeability |
| Half-Life Model Output | model output | 0.8422 | Model output only, not in-vivo half-life |