Back to Isotope Catalog
R-10035

Vitamine E (D9)

Stable isotope standard for analytical research and method development.

Module Type
Stable Isotope Standards
Category
Metabolites
CAS
131230-17-6
Unlabeled CAS
10191-41-0
PubChem CID
12359169
Molecular Formula
C29H41D9O2
Molecular Weight
439.8
AI Isotope Property & Application AnalysisShow

Isotope Summary

Labels
D9
Labeled atoms
9
Isotope positions
Confirmed in structure
Calculation reliability
High, based on explicit isotope structure

Mass & MS Parameters

Unlabeled exact mass
430.381081 Da
Labeled exact mass
439.437572 Da
Exact mass shift
9.056491 Da
Nominal mass shift
9
Ionm/zStatus
[M+H]+440.444848Theoretical
[M+Na]+462.42679Theoretical
[M+NH4]+457.471395Theoretical
[M-H]-438.430295Theoretical

Label Stability

Overall
Moderate risk
Calculation reliability
Medium, some information should be confirmed
  • Carbon-bound deuterium is evaluated by local chemical environment; isotope effects should still be checked experimentally.

Internal Standard Suitability

Rating
Medium
Chromatographic similarity
Possible isotope effect
Natural isotope overlap
Low
  • Exact mass separation is 9.056491 Da; MS channel separation should be verified in the final method.
  • The unlabeled parent mass was derived from the isotope structure because a curated parent structure was not matched.
  • Overall suitability: Medium.

Recommended Applications

LC-MS/MS Quantitative Internal Standard
Recommended

LC-MS/MS Quantitative Internal Standard is classified as Recommended based on isotope mapping, mass separation, and label-stability rules.

Isotope Dilution Mass Spectrometry
Recommended

Isotope Dilution Mass Spectrometry is classified as Recommended based on isotope mapping, mass separation, and label-stability rules.

GC-MS Internal Standard
Possible

GC-MS Internal Standard is classified as Possible based on isotope mapping, mass separation, and label-stability rules.

Bioanalytical Method Development
Recommended

Bioanalytical Method Development is classified as Recommended based on isotope mapping, mass separation, and label-stability rules.

AI Interpretation

This analysis is based on isotope-aware structure data. The compound contains D9, with an exact mass shift of 9.056491 Da. Label stability is assessed as Moderate risk, and internal-standard suitability is Medium. These results support analytical method development and require experimental validation.

AI-assisted analytical guidance is intended for method-development support. Actual isotope stability, chromatographic behavior, fragmentation and MRM transitions should be experimentally validated.